Article
Association of uncoupling protein (Ucp) gene polymorphisms with cardiometabolic diseases.
Molecular medicine (Cambridge, Mass.) - 25 May 2020
Pravednikova Anna E, Shevchenko Sergey Y, Kerchev Victor V, Skhirtladze Manana R, Larina Svetlana N, Kachaev Zaur M, Egorov Alexander D, Shidlovskii Yulii V
Abstract excerpt
The hereditary aspect of obesity is a major focus of modern medical genetics. The genetic background is known to determine a higher-than-average prevalence of obesity in certain regions, like Oceania. There is evidence that dysfunction of brown adipose tissue (BAT) may be a risk factor for obesity and type 2 diabetes (T2D). A significant number of studies in the field focus on the UCP family. The Ucp genes code...
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