Article
UCP1, the mitochondrial uncoupling protein of brown adipocyte: A personal contribution and a historical perspective.
Biochimie - 1 Mar 2017
Ricquier Daniel
Abstract excerpt
The present text summarizes what was my contribution, starting in 1975, to the research on the uncoupling protein 1 (UCP1), the mitochondrial uncoupler of brown adipocytes. The research on UCP1 aimed at identifying the mechanisms of heat production by brown adipocytes that occurs in mammals either at birth or during cold exposure and arousal in hibernators. With others and in particular Dr. David Nicholls, I...
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