Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Metabolic phenotype in the mouse model of osteogenesis imperfecta.

The Journal of endocrinology - 1 Sept 2017

Boraschi-Diaz Iris, Tauer Josephine T, El-Rifai Omar, Guillemette Delphine, Lefebvre Geneviève, Rauch Frank, Ferron Mathieu, Komarova Svetlana V

Abstract excerpt

Osteogenesis imperfecta (OI) is the most common heritable bone fragility disorder, usually caused by dominant mutations in genes coding for collagen type I alpha chains, COL1A1 or COL1A2 Osteocalcin (OCN) is now recognized as a bone-derived regulator of insulin secretion and sensitivity and glucose homeostasis. Since OI is associated with increased rates of bone formation and resorption, we hypothesized that the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Collagen Type I
Share to Disease Models, Animal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Osteocalcin

Share to Osteogenesis Imperfecta

Share to Phenotype

Source

Identifiers

PMID: 28716975
DOI: 10.1530/JOE-17-0335

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Metabolic phenotype in the mouse model of osteogenesis imperfecta.PMID 28716975Read ↗

Osteocalcin-dependent and -independent metabolic dysregulation in a mouse model of Osteogenesis imperfecta.Semantic proximity Read ↗

Makings of a brittle bone: Unexpected lessons from a low protein diet study of a mouse OI model.Semantic proximity Read ↗

An Osteocalcin-deficient mouse strain without endocrine abnormalitiesSemantic proximity Read ↗

The material basis for reduced mechanical properties in oim mice bones.Semantic proximity Read ↗

Exploring the impact of collagen-I genetic variants on intestinal structure and gut microbiota in mouse models of osteogenesis imperfecta.Semantic proximity Read ↗

Oim mice exhibit altered femur and incisor mineral composition and decreased bone mineral density.Semantic proximity Read ↗

Increased bone density in mice lacking the proton receptor OGR1.Semantic proximity Read ↗

A Complex Role for Lipocalin 2 in Bone Metabolism: Global Ablation in Mice Induces Osteopenia Caused by an Altered Energy Metabolism.Semantic proximity Read ↗

Diet-Induced Metabolic Dysregulation in Female Mice Causes Osteopenia in Adult OffspringSemantic proximity Read ↗

Postnatal loss of the insulin receptor in osteoprogenitor cells does not impart a metabolic phenotype.Semantic proximity Read ↗

Craniofacial allometry in the OIM-/- mouse model of osteogenesis imperfecta.Semantic proximity Read ↗

Bone geometry and strength measurements in aging mice with the oim mutation.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.