Article
An Osteocalcin-deficient mouse strain without endocrine abnormalities
2019-08-13
Abstract excerpt
Osteocalcin (OCN), the most abundant non-collagenous protein in the bone matrix, is reported to be a bone-derived endocrine hormone with wide-ranging effects on many aspects of physiology, including glucose metabolism and male fertility. Many of these observations were made using an OCN-deficient mouse allele (Osc - ) in which the 2 OCN-encoding genes in mice, Bglap and Bglap2 , were deleted in ES cells by homo...
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Identifiers and source
- Literature Corpus work
- e43e5834-f918-580d-8e51-a87a645ffb04
- DOI
- 10.1101/732800