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Article

Clinical features and prognostic impact of PRDM16 expression in adult acute myeloid leukemia.

Genes, chromosomes & cancer - 1 Nov 2017

Yamato Genki, Yamaguchi Hiroki, Handa Hiroshi, Shiba Norio, Kawamura Machiko, Wakita Satoshi, Inokuchi Koiti, Hara Yusuke, Ohki Kentaro, Okubo Jun, Park Myoung-Ja, Sotomatsu Manabu, Arakawa Hirokazu, Hayashi Yasuhide

Abstract excerpt

High PRDM16 (also known as MEL1) expression is a representative marker of acute myeloid leukemia (AML) with NUP98-NSD1 and is a significant predictive marker for poor prognosis in pediatric AML. However, the clinical features of adult AML with PRDM16 expression remain unclear. PRDM16 is highly homologous to MDS1/EVI1, which is an alternatively spliced transcript of MECOM (also known as EVI1). We investigated...

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Share to DNA (Cytosine-5-)-Methyltransferases
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 28710806
DOI: 10.1002/gcc.22483

Genes

PRDM16
ABL1
FLT3
MECOM
NPM1
NSD1
NUP98

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Clinical features and prognostic impact of PRDM16 expression in adult acute myeloid leukemia.PMID 28710806Read ↗

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