Article

Differential Expression of PRDM16 and PRDM14 in Myeloproliferative Neoplasms as Compared to Normal Bone Marrow: A Pilot Study

2025-09-23

Abstract excerpt

PRDM family transcription factors have been implicated in hematopoietic regulation, yet their expression in classical Philadelphia-negative myeloproliferative neoplasms (MPNs) remains unexplored. We investigated PRDM14 and PRDM16 expression in bone marrow samples from MPN patients and controls to assess associations with proliferative activity. Bone marrow trephine biopsies were obtained from 11 cases (5 with norm...

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Literature Corpus work: 451c1057-836d-50c7-9a5c-045b9ceff01e
DOI: 10.20944/preprints202509.1913.v1

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