Article
Use of haplotypes to identify regions harbouring lethal recessive variants in pigs.
Genetics, selection, evolution : GSE - 14 Jul 2017
Howard David M, Pong-Wong Ricardo, Knap Pieter W, Woolliams John A
Abstract excerpt
BACKGROUND: Lethal recessive genetic variants are maintained at relatively low frequencies in a population in the heterozygous state, but by definition are fatal and therefore unobserved in the homozygous state. Since haplotypes allow the tagging of rare and untyped genetic variants, they have potential for studying lethal recessive variants. In this study, we used a large commercial population to identify...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.