Article
Characterization of a haplotype-reference panel for genotyping by low-pass sequencing in Swiss Large White pigs.
BMC genomics - 21 Apr 2021
Nosková Adéla, Bhati Meenu, Kadri Naveen Kumar, Crysnanto Danang, Neuenschwander Stefan, Hofer Andreas, Pausch Hubert
Abstract excerpt
BACKGROUND: The key-ancestor approach has been frequently applied to prioritize individuals for whole-genome sequencing based on their marginal genetic contribution to current populations. Using this approach, we selected 70 key ancestors from two lines of the Swiss Large White breed that have been selected divergently for fertility and fattening traits and sequenced their genomes with short paired-end reads....
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