Novel harmful recessive haplotypes identified for fertility traits in Nordic Holstein cattle.

doi:10.1371/journal.pone.0082909

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Article

Novel harmful recessive haplotypes identified for fertility traits in Nordic Holstein cattle.

PloS one - 1 Jan 2013

Sahana Goutam, Nielsen Ulrik Sander, Aamand Gert Pedersen, Lund Mogens Sandø, Guldbrandtsen Bernt

Abstract excerpt

Using genomic data, lethal recessives may be discovered from haplotypes that are common in the population but never occur in the homozygote state in live animals. This approach only requires genotype data from phenotypically normal (i.e. live) individuals and not from the affected embryos that die. A total of 7,937 Nordic Holstein animals were genotyped with BovineSNP50 BeadChip and haplotypes including 25...

Topics

Animals
Breeding
Cattle
Female
Fertility
Genes, Lethal
Genetic Markers
Genotyping Techniques
Haplotypes
Heterozygote
Homozygote
Male
Phenotype
Polymorphism, Single Nucleotide

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Identifiers

PMID: 24376603
DOI: 10.1371/journal.pone.0082909
PMCID: PMC3869739

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