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Article

Effect of genomic regions harboring putative lethal haplotypes on reproductive performance in closed experimental selection lines of Nellore cattle.

Scientific reports - 3 Feb 2025

Rodrigues Gustavo R D, Cyrillo Joslaine N S G, Mota Lúcio F M, Schmidt Patrícia I, Valente Júlia P S, Oliveira Eduarda S, Albuquerque Lúcia G, Brito Luiz F, Mercadante Maria E Z

Abstract excerpt

Lethal alleles are mutations in the genome that cause embryonic losses in affected homozygous embryos and, therefore, can negatively influence reproduction rates in commercial populations. Thus, this study aimed to identify genomic regions containing potential lethal haplotypes in Nellore breed; identify candidate genes located within these regions; and investigate the reproductive performance of heterozygous...

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Identifiers

PMID: 39900660
DOI: 10.1038/s41598-025-88501-7
PMCID: PMC11791054

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