Article
A systematic survey to identify lethal recessive variation in highly managed pig populations.
BMC genomics - 9 Nov 2017
Derks Martijn F L, Megens Hendrik-Jan, Bosse Mirte, Lopes Marcos S, Harlizius Barbara, Groenen Martien A M
Abstract excerpt
BACKGROUND: Lethal recessive variation can cause prenatal death of homozygous offspring. Although usually present at low-frequency in populations, the impact on individual fitness can be substantial. Until recently, the presence of recessive embryonic lethal variation could only be measured indirectly through reduced fertility. In this study, we estimate the presence of genetic loci associated with both early and...
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