Article
Linked PNPLA3 polymorphisms confer susceptibility to nonalcoholic steatohepatitis and decreased viral load in chronic hepatitis B.
World journal of gastroenterology - 28 Jul 2015
Pan Qin, Zhang Rui-Nan, Wang Yu-Qin, Zheng Rui-Dan, Mi Yu-Qiang, Liu Wen-Bin, Shen Feng, Chen Guang-Yu, Lu Jia-Fa, Zhu Chan-Yan, Zhang Shu-Yi, Chen Yi-Ming, Sun Wan-Lu, Fan Jian-Gao
Abstract excerpt
AIM: To investigate the association of PNPLA3 polymorphisms with concurrent chronic hepatitis B (CHB) and nonalcoholic fatty liver disease (NAFLD). METHODS: A cohort of Han patients with biopsy-proven CHB, with or without NAFLD (CHB group, n = 51; CHB + NAFLD group, n = 57), and normal controls (normal group, n = 47) were recruited from Northern (Tianjin), Central (Shanghai), and Southern (Zhangzhou) China. Their...
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