Article
PNPLA3 rs738409 causes steatosis according to viral & IL28B genotypes in hepatitis C.
Annals of hepatology - 1 Jan 2000
Ampuero Javier, Del Campo José A, Rojas Lourdes, García-Lozano José R, Solá Ricard, Andrade Raúl, Pons José A, Navarro José M, Calleja José L, Buti María, González-Escribano María F, Forns Xavier, Diago Moisés, García-Samaniego Javier, Romero-Gómez Manuel
Abstract excerpt
BACKGROUND: Hepatitis C virus (HCV) is associated with a higher prevalence of steatosis compared to the general population. AIM: Our aim was to assess the impact of PNPLA3 rs738409 G-allele on steatosis in HCV patients. MATERIAL AND METHODS: We included 474 HCV patients treated with peginterferon plus ribavirin. PNPLA3 rs738409 was genotyped and patients were classified according to alleles and genotypes....
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