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Article

APOC3 rs2070666 Is Associated with the Hepatic Steatosis Independently of PNPLA3 rs738409 in Chinese Han Patients with Nonalcoholic Fatty Liver Diseases.

Digestive diseases and sciences - 1 Aug 2016

Zhang Rui-Nan, Zheng Rui-Dan, Mi Yu-Qiang, Zhou Da, Shen Feng, Chen Guang-Yu, Zhu Chan-Yan, Pan Qin, Fan Jian-Gao

Abstract excerpt

BACKGROUND AND AIM: The association between nonalcoholic fatty liver disease (NAFLD) and apolipoprotein C3 gene (APOC3) promoter region single-nucleotide polymorphisms (SNPs) rs2854117 and rs2854116 is controversial. The aim of this study was to investigate the relationship between other polymorphisms of APOC3 and NAFLD in Chinese. METHODS: Fifty-nine liver biopsy-proven NAFLD patients and 72 healthy control...

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Source

Identifiers

PMID: 27059980
DOI: 10.1007/s10620-016-4120-7

Genes

APOC3
PNPLA3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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APOC3 rs2070666 Is Associated with the Hepatic Steatosis Independently of PNPLA3 rs738409 in Chinese Han Patients with Nonalcoholic Fatty Liver Diseases.PMID 27059980Read ↗

PNPLA3 polymorphisms (rs738409) and non-alcoholic fatty liver disease risk and related phenotypes: a meta-analysis.Semantic proximity Read ↗

Genetic variants in PNPLA3 and risk of non-alcoholic fatty liver disease in a Han Chinese population.Semantic proximity Read ↗

Association of the rs738409 polymorphism in PNPLA3 with liver damage and the development of nonalcoholic fatty liver disease.Semantic proximity Read ↗

Association between APOC3 polymorphisms and non-alcoholic fatty liver disease risk: a meta-analysis.Semantic proximity Read ↗

Association between PNPLA3 rs738409 polymorphism and nonalcoholic fatty liver disease (NAFLD) susceptibility and severitySemantic proximity Read ↗

Association of patatin-like phospholipase domain-containing protein 3 gene polymorphisms with susceptibility of nonalcoholic fatty liver disease in a Han Chinese population.Semantic proximity Read ↗

I148M variant of PNPLA3 increases the susceptibility to non-alcoholic fatty liver disease caused by obesity and metabolic disorders.Semantic proximity Read ↗

APOC3 rs2070667 Associates with Serum Triglyceride Profile and Hepatic Inflammation in Nonalcoholic Fatty Liver Disease.Semantic proximity Read ↗

Role of the PNPLA3 I148M polymorphism in nonalcoholic fatty liver disease and fibrosis in Korea.Semantic proximity Read ↗

[Polymorphism rs738409 in PNPLA3 is associated with inherited susceptibility to non-alcoholic fatty liver disease].Semantic proximity Read ↗

A gene variant of PNPLA3, but not of APOC3, is associated with histological parameters of NAFLD in an obese population.Semantic proximity Read ↗

Association Between the PNPLA3 rs738409 Polymorphism and Susceptibility to Non-Alcoholic Fatty Liver Disease: A Systematic Review and Ethnicity-Stratified Meta-analysisSemantic proximity Read ↗

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