Article
Innexins: members of an evolutionarily conserved family of gap-junction proteins.
Biochimica et biophysica acta - 10 Jun 2005
Phelan Pauline
Abstract excerpt
Gap junctions are clusters of intercellular channels that provide cells, in all metazoan organisms, with a means of communicating directly with their neighbours. Surprisingly, two gene families have evolved to fulfil this fundamental, and highly conserved, function. In vertebrates, gap junctions are assembled from a large family of connexin proteins. Innexins were originally characterized as the structural...
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