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Efficient generation of goats with defined point mutation (I397V) in GDF9 through CRISPR/Cas9.

Reproduction, fertility, and development - 1 Jan 2018

Niu Yiyuan, Zhao Xiaoe, Zhou Jiankui, Li Yan, Huang Yu, Cai Bei, Liu Yutai, Ding Qiang, Zhou Shiwei, Zhao Jin, Zhou Guangxian, Ma Baohua, Huang Xingxu, Wang Xiaolong, Chen Yulin

Abstract excerpt

The recent emergence of the clustered regularly interspaced short palindromic repeat (CRISPR)/CRISPR-associated (Cas) 9 system has attracted significant attention for its potential to improve traits of agricultural importance. However, most applications in livestock species to date have depended on aberrant DNA repair to generate frameshifting indels. Whether this genomic engineering technique involving...

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PMID: 28692815
DOI: 10.1071/RD17068

Genes

GDF9

Variants

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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