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Article

SPARC gene variants predict clinical outcome in locally advanced and metastatic pancreatic cancer patients.

Medical oncology (Northwood, London, England) - 1 Aug 2017

Arqueros Cristina, Salazar Juliana, Arranz M J, Sebio Ana, Mora Josefina, Sullivan Ivana, Tobeña María, Martín-Richard Marta, Barnadas Agustí, Baiget Montserrat, Páez David

Abstract excerpt

Secreted protein acidic and rich in cysteine (SPARC) is a glycoprotein of the extracellular matrix whose expression can be altered in malignant pancreatic cells and in the adjacent stromal fibroblasts. We evaluated the possible role of SPARC gene variants as prognostic markers for locally advanced and metastatic pancreatic cancer. We analyzed eight tagging single-nucleotide polymorphisms (TagSNPs) in the SPARC...

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Source

Identifiers

PMID: 28687963
DOI: 10.1007/s12032-017-0993-3

Genes

SPARC
MAF

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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