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Article

An individual coding polymorphism and the haplotype of the SPARC gene predict gastric cancer recurrence.

The pharmacogenomics journal - 1 Aug 2013

Winder T, Wilson P M, Yang D, Zhang W, Ning Y, Power D G, Bohanes P, Gerger A, Tang L H, Shah M, Lenz H-J

Abstract excerpt

The 5-year survival rate for gastric adenocarcinoma (GA) remains only 40% and biomarkers to identify patients at high risk of tumor recurrence are urgently needed. Secreted protein acidic and rich in cysteine (SPARC) is an extracellular matrix glycoprotein that mediates cell matrix interactions, and upregulation of SPARC can promote tumor progression and metastasis. This study investigated whether...

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Source

Identifiers

PMID: 22491017
DOI: 10.1038/tpj.2012.11

Genes

SPARC
TTR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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