Association of genetic polymorphisms with survival of pancreatic ductal adenocarcinoma patients.

doi:10.1093/carcin/bgw080

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Article

Association of genetic polymorphisms with survival of pancreatic ductal adenocarcinoma patients.

Carcinogenesis - 1 Oct 2016

Rizzato Cosmeri, Campa Daniele, Talar-Wojnarowska Renata, Halloran Christopher, Kupcinskas Juozas, Butturini Giovanni, Mohelníková-Duchoňová Beatrice, Sperti Cosimo, Tjaden Christine, Ghaneh Paula, Hackert Thilo, Funel Niccola, Giese Nathalia, Tavano Francesca, Pezzilli Raffaele, Pedata Mariangela, Pasquali Claudio, Gazouli Maria, Mambrini Andrea, Souček Pavel, di Sebastiano Pierluigi, Capurso Gabriele, Cantore Maurizio, Oliverius Martin, Offringa Rienk, Małecka-Panas Ewa, Strobel Oliver, Scarpa Aldo, Canzian Federico

Abstract excerpt

Germline genetic variability might contribute, at least partially, to the survival of pancreatic ductal adenocarcinoma (PDAC) patients. Two recently performed genome-wide association studies (GWAS) on PDAC overall survival (OS) suggested (P < 10(-5)) the association between 30 genomic regions and PDAC OS. With the aim to highlight the true associations within these regions, we analyzed 44 single-nucleotide...

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PMID: 27497070
DOI: 10.1093/carcin/bgw080

Genes

CTNNA2
RUNX2

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