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Article

BRCA1 missense polymorphisms are associated with poor prognosis of pancreatic cancer patients in a Chinese population.

Oncotarget - 30 May 2017

Zhu Ying, Zhai Kan, Ke Juntao, Li Jiaoyuan, Gong Yajie, Yang Yang, Tian Jianbo, Zhang Yi, Zou Danyi, Peng Xiating, Gong Jing, Zhong Rong, Huang Kun, Chang Jiang, Miao Xiaoping

Abstract excerpt

Pancreatic cancer is a highly lethal disease with limited prognostic marker. BRAC1 and BRCA2 are two classic tumor suppressor genes which play an important role in DNA repair. Somatic mutations and germline genetic variants on BRCA1/2 have been found associated with the tumorigenesis of pancreatic cancer. However, the correlations between BRCA1/2 polymorphism and pancreatic cancer prognosis remained unknown. In...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 28415599
DOI: 10.18632/oncotarget.16422
PMCID: PMC5482636

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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