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Article

Age-related accumulation of phosphorylated mitofusin 2 protein in retinal ganglion cells correlates with glaucoma progression.

Experimental neurology - 1 Oct 2017

Nivison Mary P, Ericson Nolan G, Green Virginia M, Bielas Jason H, Campbell Jean S, Horner Philip J

Abstract excerpt

Dysregulation of axonal bioenergetics is likely a key mechanism in the initiation and progression of age-related neurodegenerative diseases. Glaucoma is a quintessential neurodegenerative disorder characterized by progressive deterioration of the optic nerve (ON) and eventual death of retinal ganglion cells (RGCs). Age and elevation of intraocular pressure are key risk factors in glaucoma, but the common early...

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Identifiers

PMID: 28684211
DOI: 10.1016/j.expneurol.2017.07.001
PMCID: PMC6021128

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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