Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Optic neuropathies: the tip of the neurodegeneration iceberg

25 Jul 2017

Abstract excerpt

The optic nerve and the cells that give origin to its 1.2 million axons, the retinal ganglion cells (RGCs), are particularly vulnerable to neurodegeneration related to mitochondrial dysfunction. Optic neuropathies may range from non-syndromic genetic entities, to rare syndromic multisystem diseases with optic atrophy such as mitochondrial encephalomyopathies, to age-related neurodegenerative diseases such as...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alzheimer's disease research and treatments
Share to Mitochondrial Function and Pathology
Share to Retinal Development and Disorders

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 28977448
DOI: 10.1093/hmg/ddx273

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Optic neuropathies: the tip of the neurodegeneration icebergPMID 28977448Read ↗

A Review of Mitochondrial Optic Neuropathies: From Inherited to Acquired FormsSemantic proximity Read ↗

Mitochondrial optic neuropathies.Semantic proximity Read ↗

Mitochondrial optic neuropathies - disease mechanisms and therapeutic strategies.Semantic proximity Read ↗

The Healthy and Diseased Retina Seen through Neuron-Glia InteractionsSemantic proximity Read ↗

Melatonin As a Modulator of Degenerative and Regenerative Signaling Pathways in Injured Retinal Ganglion CellsSemantic proximity Read ↗

Mitochondrial disorders of the retinal ganglion cells and the optic nerve.Semantic proximity Read ↗

Mitochondrial optic neuropathies: how two genomes may kill the same cell type?Semantic proximity Read ↗

Cellular and molecular alterations in neurons and glial cells in inherited retinal degenerationSemantic proximity Read ↗

Insights on the Genetic and Phenotypic Complexities of Optic Neuropathies.Semantic proximity Read ↗

Mitochondrial Membrane Dynamics and Inherited Optic Neuropathies.Semantic proximity Read ↗

Hereditary Optic Neuropathies: From the Mitochondria to the Optic NerveSemantic proximity Read ↗

[Leber hereditary optic neuropathy: update on genetics and pathomechanisms].Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.