Article
Genetic factors and multiple sclerosis in the Moroccan population: a role for HLA class II.
Pathologie-biologie - 1 Dec 2013
Ouadghiri S, El Alaoui Toussi K, Brick C, Ait Benhaddou E H, Benseffaj N, Benomar A, El Yahyaoui M, Essakalli M
Abstract excerpt
BACKGROUND AND OBJECTIVE: Multiple sclerosis (MS) is an autoimmune inflammatory demyelinating disease of the central nervous system that mainly affects young adults. The association between susceptibility to MS and HLA class II genes, in particular the DRB1*15 allele, has been reported in diverse ethnic groups. The aim of our study was to investigate the distribution of HLA-DRB1* and -DQB1* alleles in Moroccan...
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