Article
Radical-Generating Activity, Phagocytosis, and Mechanical Properties of Four Phenotypes of Human Macrophages.
International journal of molecular sciences - 3 Feb 2024
Suleimanov Shakir K, Efremov Yuri M, Klyucherev Timofey O, Salimov Emin L, Ragimov Aligeydar A, Timashev Peter S, Vlasova Irina I
Abstract excerpt
Macrophages are the major players and orchestrators of inflammatory response. Expressed proteins and secreted cytokines have been well studied for two polar macrophage phenotypes-pro-inflammatory M1 and anti-inflammatory regenerative M2, but little is known about how the polarization modulates macrophage functions. In this study, we used biochemical and biophysical methods to compare the functional activity and...
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