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[Anti-inflammation of simvastatin by polarization of murine macrophages from M1 phenotype to M2 phenotype].

Zhonghua yi xue za zhi - 9 Jul 2013

Li Quan-zhong, Sun Jing, Han Jin-jie, Qian Zong-jie

Abstract excerpt

OBJECTIVE: To explore the effects of statin on pro-inflammatory macrophage phenotype in a murine M1 macrophage model. METHODS: Macrophages isolated from murine bone barrow were stimulated with interferon-gamma (IFN-γ) and lipopolysaccharide (LPS) to establish a M1 macrophage model. And 1.0, 2.5, 5.0 µmol/L of simvastatin were added to M1 macrophages for a 9-hour culture. Cell surface markers CD16/23 and CD206...

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PMID: 24169290

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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