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Article

Studying structure and function of spliceosomal helicases.

Methods (San Diego, Calif.) - 1 Aug 2017

Ficner Ralf, Dickmanns Achim, Neumann Piotr

Abstract excerpt

The splicing of eukaryotic precursor mRNAs requires the activity of at least three DEAD-box helicases, one Ski2-like helicase and four DEAH-box helicases. High resolution structures for five of these spliceosomal helicases were obtained by means of X-ray crystallography. Additional low resolution structural information could be derived from single particle cryo electron microscopy and small angle X-ray...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 28668587
DOI: 10.1016/j.ymeth.2017.06.028

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026.

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