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Article

Three-dimensional structure of C complex spliceosomes by electron microscopy.

Nature structural & molecular biology - 1 Mar 2004

Jurica Melissa S, Sousa Duncan, Moore Melissa J, Grigorieff Nikolaus

Abstract excerpt

The spliceosome is a multimegadalton RNA-protein machine that removes noncoding sequences from nascent pre-mRNAs. Recruitment of the spliceosome to splice sites and subsequent splicing require a series of dynamic interactions among the spliceosome's component U snRNPs and many additional protein...

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Identifiers

PMID: 14981503
DOI: 10.1038/nsmb728

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-14981503-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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