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Article

Crystal structure of the human ATP-dependent splicing and export factor UAP56.

Proceedings of the National Academy of Sciences of the United States of America - 21 Dec 2004

Shi Hang, Cordin Olivier, Minder C Michael, Linder Patrick, Xu Rui-Ming

Abstract excerpt

Pre-mRNA splicing requires the function of a number of RNA-dependent ATPases/helicases, yet no three-dimensional structure of any spliceosomal ATPases/helicases is known. The highly conserved DECD-box protein UAP56/Sub2 is an essential splicing factor that is also important for mRNA export. The expected ATPase/helicase activity appears to be essential for the UAP56/Sub2 functions. Here, we show that purified...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 15585580
DOI: 10.1073/pnas.0408172101
PMCID: PMC539749

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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