Article
A plate-based histo-blood group antigen binding assay for evaluation of human norovirus receptor binding ability.
Analytical biochemistry - 15 Sept 2017
Moore Matthew D, Jaykus Lee-Ann
Abstract excerpt
Human norovirus is a leading cause of gastroenteritis worldwide. Although two in vitro cultivation methods have been reported, they cannot provide mechanistic insights into viral inactivation. Receptor-binding assays supplement these assays and give insight into capsid integrity. We present a streamlined version of a receptor-binding assay with minimal time-to-result while maintaining accuracy and high...
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