A Bacterial Surface Display System Expressing Cleavable Capsid Proteins of Human Norovirus: A Novel System to Discover Candidate Receptors

Abstract excerpt

Human noroviruses (HuNoVs) are the dominant cause of food-borne outbreaks of acute gastroenteritis. However, fundamental researches on HuNoVs, such as identification of viral receptors have been limited by the currently immature system to culture HuNoVs and the lack of efficient small animal models. Previously, we demonstrated that the recombinant protruding domain (P domain) of HuNoVs capsid proteins were...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Escherichia coli research studies
• Share to Viral gastroenteritis research and epidemiology
• Share to Virus-based gene therapy research