Article

Characterization of high affinity IgM and IgG monoclonal antibodies against norovirus variants GII.4 and GII.17

2024-05-12

Abstract excerpt

Human norovirus, a leading cause of viral gastroenteritis, results in significant global health and economic burden, requiring sensitive and accurate diagnosis and effective therapeutics and vaccines. In this study, we immunized mice with the virus like capsid particles of GII.4, a mainstream strain, and GII.17, a modern strain that began to circulate in 2014, and used hybridoma technology to generate hybridoma ce...

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Literature Corpus work: dde60c0b-de9f-52a7-9f8e-10d2f23a4066
DOI: 10.1101/2024.05.11.593658

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