Article
Macrophage Migration Inhibitory Factor (MIF) Gene Promotor Polymorphism Is Associated with Increased Fibrosis in Biliary Atresia Patients, but Not with Disease Susceptibility.
Annals of human genetics - 1 Sept 2017
Sadek Khaled H, Ezzat Sameera, Abdel-Aziz Samira A, Alaraby Hanaa, Mosbeh Asmaa, Abdel-Rahman Mohamed H
Abstract excerpt
Two polymorphisms, rs755622 and rs5844572, in the promoter region of the macrophage migration inhibitory factor (MIF) gene influence the basal and/or induced transcriptional activity and have been linked to several inflammatory and autoimmune diseases. The aim of this study was to investigate the association between these two polymorphisms and disease susceptibility in patients with biliary atresia (BA). Allele...
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