Article
The role of macrophage migration inhibitory factor in autoimmune liver disease.
Hepatology (Baltimore, Md.) - 1 Feb 2014
Assis David N, Leng Lin, Du Xin, Zhang Clarence K, Grieb Gerrit, Merk Melanie, Garcia Alvaro Baeza, McCrann Catherine, Chapiro Julius, Meinhardt Andreas, Mizue Yuka, Nikolic-Paterson David J, Bernhagen Jürgen, Kaplan Marshall M, Zhao Hongyu, Boyer James L, Bucala Richard
Abstract excerpt
UNLABELLED: The role of the cytokine, macrophage migration inhibitory factor (MIF), and its receptor, CD74, was assessed in autoimmune hepatitis (AIH) and primary biliary cirrhosis (PBC). Two MIF promoter polymorphisms, a functional -794 CATT5-8 microsatellite repeat (rs5844572) and a -173 G/C single-nucleotide polymorphism (rs755622), were analyzed in DNA samples from over 500 patients with AIH, PBC, and...
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