Article
Polymorphism of ITGB2 gene 3'-UTR+145C/A is associated with biliary atresia.
Digestion - 1 Jan 2013
Zhao Rui, Song Zai, Dong Rui, Li Hao, Shen Chun, Zheng Shan
Abstract excerpt
BACKGROUND AND STUDY AIMS: Biliary atresia (BA) is a devastating disease of infants, invariably leading to cirrhosis, end-stage liver disease, and death if untreated. The etiology of BA is unknown, although infectious, immune, and genetic causes have been suggested. This study was designed to investigate whether polymorphism of the ITGB2 (CD18) gene is associated with susceptibility to BA. METHODS: The ITGB2 gene...
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