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Article

PDGFA gene rs9690350 polymorphism increases biliary atresia risk in Chinese children.

Bioscience reports - 31 Jul 2020

Liu Fei, Zeng Jixiao, Zhu Deli, Xu Xiaogang, Lan Menglong, Wang Mengmeng, Zhao Jinglu, Xia Huimin, Zhang Yan, Zhang Ruizhong

Abstract excerpt

Biliary atresia (BA) is a genetic and severe fibro-inflammatory obliterative cholangiopathy of neonates. Platelet-derived growth factor subunit A (PDGFA), as one of participants in liver fibrosis, the overexpression of PDGFA through DNA hypomethylation may lead to the development of BA, but the pathogenesis is still unclear. We conducted a large case-control cohort to investigate the association of genetic...

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Identifiers

PMID: 32662506
DOI: 10.1042/BSR20200068
PMCID: PMC7374268

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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