Article
MiR-100 rs1834306 A>G Increases Biliary Atresia Risk in Southern Han Chinese Children.
BioMed research international - 1 Jan 2023
Chang Jiaming, Liang Jiankun, Chai Chengwei, Liu Fei, Tao Boyuan, Wang Hezhen, Tong Yanlu, Wang Zhe, Xia Huimin
Abstract excerpt
Background: Biliary atresia (BA) is a type of severe cholestatic childhood disease that may have a genetic component. miR-100 plays a key role in regulating cell apoptosis, proliferation, and inflammatory reactions. A single-nucleotide polymorphism in miR-100 has been proven to modulate susceptibility to various diseases. Methods: We conducted a case-control retrospective study to explore the correlation between...
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