Article
The association of immune-related genes and the potential role of IL10 with biliary atresia.
Pediatric research - 1 Nov 2023
Lin Zefeng, Tian Yan, Chai Chengwei, Fu Ming, Wu Qi, Tan Ledong, Li Le, Guan Xisi, Wang Zhe, Zhao Jinglu, Wang Hezhen, Tong Yanlu, Zhang Yan, Zhang Ruizhong
Abstract excerpt
BACKGROUND: Biliary atresia (BA) is a severe immune-related disease that is characterized by biliary obstruction and cholestasis. The etiology of BA is unclear, our aim was to explore the relationship between biliary tract inflammation and immune-related genes. METHODS: We selected 14 SNPs in 13 immune-related genes and investigated their associations with BA by using a large case‒control cohort with a total of...
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