Upstream stimulatory factor 2 is implicated in the progression of biliary atresia by regulation of hepcidin expression.

doi:10.1016/j.jpedsurg.2008.03.037

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Community

Back to search

Article

Upstream stimulatory factor 2 is implicated in the progression of biliary atresia by regulation of hepcidin expression.

Journal of pediatric surgery - 1 Nov 2008

Huang Ying-Hsien, Huang Chao-Cheng, Chuang Jiin-Haur, Hsieh Chie-Sung, Lee Shin-Ye, Chen Chao-Long

Abstract excerpt

BACKGROUND: Hepcidin is downregulated during the progression of biliary atresia (BA), but the mechanism is still unknown. METHODS: We analyzed single nucleotide polymorphism of rs7251432 and 916145 within hepcidin and its upstream, USF2 gene, respectively, in 52 patients of BA and 96 healthy controls. Liver tissues were obtained from 10 patients with early and late stage of BA, 10 patients with choledochal cyst,...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Active Transport, Cell Nucleus

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Antimicrobial Cationic Peptides

Share to Biliary Atresia

Share to Chromatin Immunoprecipitation

Share to Gene Knockdown Techniques

Share to Hepatocytes

Share to Hepcidins

Share to Upstream Stimulatory Factors

Source

Open in PubMed

Identifiers

PMID: 18970934
DOI: 10.1016/j.jpedsurg.2008.03.037

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Upstream stimulatory factor 2 is implicated in the progression of biliary atresia by regulation of hepcidin expression.PMID 18970934Read ↗

Irrelevance of USF2 rs916145 polymorphism with the risk of biliary atresia susceptibility in Southern Chinese children.Semantic proximity Read ↗

Immune and genetic landscapes of biliary atresia: a pathway to precision medicine.Semantic proximity Read ↗

Genome-wide association study identifies a susceptibility locus for biliary atresia on 10q24.2.Semantic proximity Read ↗

A genome-wide association study identifies a susceptibility locus for biliary atresia on 2p16.1 within the gene EFEMP1.Semantic proximity Read ↗

Deletion of interleukin enhancer binding factor 2 (ILF2) resulted in defective biliary development and bile flow blockageSemantic proximity Read ↗

Serum microRNA microarray analysis identifies miR-4429 and miR-4689 are potential diagnostic biomarkers for biliary atresiaSemantic proximity Read ↗

Identifying Biomarkers to Predict the Prognosis of Biliary Atresia by Weighted Gene Co-Expression Network AnalysisSemantic proximity Read ↗

Loci Associated With Susceptibility to Biliary Atresia-A Genome-Wide Association Study in Taiwan.Semantic proximity Read ↗

MiR-100 rs1834306 A>G Increases Biliary Atresia Risk in Southern Han Chinese Children.Semantic proximity Read ↗

Macrophage Migration Inhibitory Factor (MIF) Gene Promotor Polymorphism Is Associated with Increased Fibrosis in Biliary Atresia Patients, but Not with Disease Susceptibility.Semantic proximity Read ↗

MicroRNA-499 Rs3746444 polymorphism and biliary atresia.Semantic proximity Read ↗

Integrative genomics identifies candidate microRNAs for pathogenesis of experimental biliary atresiaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.