Article
Association of polymorphism in the VEGFA gene 3'-UTR +936T/C with susceptibility to biliary atresia in a Southern Chinese Han population.
Journal of clinical laboratory analysis - 1 May 2018
Liu Fei, Zeng Jixiao, Zhu Deli, Zhang Ruizhong, Xu Xiaogang, Wang Mengmeng, Zhang Yan, Xia Huimin, Feng Zhichun
Abstract excerpt
BACKGROUND: Biliary atresia (BA) is a neonatal disease characterized by chronic inflammation of the bile ducts and progressive aggravation of jaundice, but with a poor prognosis and high mortality. The etiology of BA is still uncertain which may be related to gene defect, virus infection, immune disorder, gene polymorphism. As a proinflammatory cytokine, VEGFA gene polymorphism (rs3025039) has been shown to be...
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