Article
Association of IL18 genetic polymorphisms with increased risk of Biliary atresia susceptibility in Southern Chinese children.
Gene - 30 Nov 2018
Liang Jiankun, Wen Zhe, Zhao Jinglu, Liang Qifeng, Liu Tao, Xia Huimin, Zhang Yan, Zhang RuiZhong
Abstract excerpt
Biliary atresia (BA) has complex genetic etiology, characterized by different levels of hepatic fibrosis after the Kasai procedure and immune responses to the bile duct. As an activator of the two most important inflammatory cells in Biliary atresia (T cells and NK cells), IL-18 is significantly increased in BA patients. This study aims to investigate the association of Interleukin 18(IL-18) with the...
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