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Article

Whole-exome sequencing reveals critical genes underlying metastasis in oesophageal squamous cell carcinoma.

The Journal of pathology - 1 Aug 2017

Dai Wei, Ko Josephine Mun Yee, Choi Sheyne Sta Ana, Yu Zhouyou, Ning Luwen, Zheng Hong, Gopalan Vinod, Chan Kin Tak, Lee Nikki Pui-Yue, Chan Kwok Wah, Law Simon Ying-Kit, Lam Alfred King-Yin, Lung Maria Li

Abstract excerpt

Oesophageal squamous cell carcinoma (ESCC) is one of the most lethal cancers, owing to a high frequency of metastasis. However, little is known about the genomic landscape of metastatic ESCC. To identify the genetic alterations that underlie ESCC metastasis, whole-exome sequencing was performed for 41 primary tumours and 15 lymph nodes (LNs) with metastatic ESCCs. Eleven cases included matched primary tumours,...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 28608921
DOI: 10.1002/path.4925

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TET2

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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