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Article

Genomic Alteration During Metastasis of Lung Adenocarcinoma.

Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology - 1 Jan 2016

Tan Qiang, Cui Jian, Huang Jia, Ding Zhengping, Lin Hao, Niu Xiaomin, Li Zhiming, Wang Guan, Luo Qingquan, Lu Shun

Abstract excerpt

BACKGROUND/AIMS: Recurrent gene mutation has been identified by the analysis of exonic DNA from lung adenocarcinoma, but its progression has not been extensively profiled. The investigation of the mutational landscape of tumors provides new insights into cancer genome evolution and further discovers the interplay of somatic mutation, adaptation of clones to their environment and natural selection. Cancer...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 26828653
DOI: 10.1159/000438644

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