Article
Whole-exome sequencing to identify somatic mutations in peritoneal metastatic gastric adenocarcinoma: A preliminary study.
Oncotarget - 12 Jul 2016
Liu Hao, Li Fengping, Zhu Yu, Li Tingting, Huang Haipeng, Lin Tian, Hu Yanfeng, Qi Xiaolong, Yu Jiang, Li Guoxin
Abstract excerpt
Peritoneal metastasis occurs in more than half of patients with unresectable or recurrent gastric cancer and is associated with the worst prognosis. The associated genomic events and pathogenesis remain ambiguous. The aim of the present study was to characterize the mutation spectrum of gastric cancer with peritoneal metastasis and provide a basis for the identification of new biomarkers and treatment targets....
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