Article
Dynamics of Islet Autoantibodies During Prospective Follow-Up From Birth to Age 15 Years.
The Journal of clinical endocrinology and metabolism - 1 Dec 2020
Pöllänen Petra M, Ryhänen Samppa J, Toppari Jorma, Ilonen Jorma, Vähäsalo Paula, Veijola Riitta, Siljander Heli, Knip Mikael
Abstract excerpt
CONTEXT: We set out to characterize the dynamics of islet autoantibodies over the first 15 years of life in children carrying genetic susceptibility to type 1 diabetes (T1D). We also assessed systematically the role of zinc transporter 8 autoantibodies (ZnT8A) in this context. DESIGN: HLA-predisposed children (N = 1006, 53.0% boys) recruited from the general population during 1994 to 1997 were observed from birth...
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