Article
Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.
Diabetologia - 1 Oct 2015
Giannopoulou Eleni Z, Winkler Christiane, Chmiel Ruth, Matzke Claudia, Scholz Marlon, Beyerlein Andreas, Achenbach Peter, Bonifacio Ezio, Ziegler Anette-G
Abstract excerpt
AIMS/HYPOTHESIS: Autoantibodies that precede type 1 diabetes frequently develop in early childhood and target distinct beta cell proteins. The aim of this study was to determine the heterogeneity of islet autoantibody development and fate. METHODS: The ages of development of insulin autoantibodies (IAA) and GAD autoantibodies (GADA), followed by multiple islet autoantibodies and progression to diabetes were...
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