Article
Associations between deduced first islet specific autoantibody with sex, age at diagnosis and genetic risk factors in young children with type 1 diabetes.
Pediatric diabetes - 1 Sept 2022
Ilonen Jorma, Laine Antti-Pekka, Kiviniemi Minna, Härkönen Taina, Lempainen Johanna, Knip Mikael
Abstract excerpt
OBJECTIVES: We aimed to further characterize demography and genetic associations of type 1 diabetes "endotypes" defined by the first appearing islet specific autoantibodies. RESEARCH DESIGN AND METHODS: We analyzed 3277 children diagnosed before the age of 10 years from the Finnish Pediatric Diabetes Register. The most likely first autoantibody could be deduced in 1636 cases (49.9%) based on autoantibody...
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