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Article

GLIS3 rs7020673 and rs10758593 polymorphisms interact in the susceptibility for type 1 diabetes mellitus.

Acta diabetologica - 1 Sept 2017

Duarte Guilherme C K, Assmann Tais S, Dieter Cristine, de Souza Bianca M, Crispim Daisy

Abstract excerpt

AIMS: The transcription factor Gli-similar 3 (GLIS3) plays a key role in the development and maintenance of pancreatic beta cells as well as in the regulation of Insulin gene expression in adults. Accordingly, genome-wide association studies identified GLIS3 as a susceptibility locus for type 1 diabetes mellitus (T1DM) and glucose metabolism traits. Therefore, the aim of this study was to replicate the...

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Source

Identifiers

PMID: 28597135
DOI: 10.1007/s00592-017-1009-7

Genes

GLIS3

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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