Article
Polymorphism of the GLIS3 gene in a Caucasian population and among individuals with carbohydrate metabolism disorders in Russia.
BMC research notes - 2 Apr 2018
Shakhtshneider E V, Mikhailova S V, Ivanoshchuk D E, Orlov P S, Ovsyannikova A K, Rymar O D, Ragino Yu I, Voevoda M I
Abstract excerpt
OBJECTIVE: Earlier, GLIS3 gene polymorphisms have been shown to be associated with the development of maturity onset diabetes of the young (MODY). We screened GLIS3 gene sequences among patients with MODY to identify probably pathogenic variants by whole-exome sequencing. We estimated frequency of rare single-nucleotide variants in the coding region of GLIS3 in a Caucasian population and among individuals with...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.