Article
Influence of ovarian cancer type I and type II microenvironment on the phenotype and function of monocyte-derived dendritic cells.
Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico - 1 Dec 2017
Surówka J, Wertel I, Okła K, Bednarek W, Tarkowski R, Kotarski J
Abstract excerpt
PURPOSE: The aim of this study was to evaluate the influence of ovarian cancer cell lysates isolated from type I or type II ovarian cancer (OC) on the phenotype of monocyte-derived dendritic cells (Mo-DCs) and the cytokine profile. We also determined whether the Mo-DCs and tumor microenvironment, reflected by peritoneal fluid (PF) from type I or II ovarian cancer, could promote regulatory T cell (Tregs)...
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