Article
Hepatic environment elicits monocyte differentiation into a dendritic cell subset directing Th2 response.
Journal of hepatology - 1 Mar 2006
Cabillic Florian, Rougier Nathalie, Basset Christelle, Lecouillard Isabelle, Quelvennec Erwann, Toujas Louis, Guguen-Guillouzo Christiane, Corlu Anne
Abstract excerpt
BACKGROUND/AIMS: Dendritic cells (DCs), which play a critical role during immune response, could present alternative differentiation patterns depending on tissue microenvironment. Our aim was to examine the influence of hepatic microenvironment on human monocyte differentiation into DCs. METHODS: Cytology, immunophenotyping, cytokine production and T-cell activation were analyzed in DCs differentiated from human...
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